Based on Qin'an LU's thought of supporting Yang with Yang as the core, and based on the on tology of Yang inside and Yin outside, under the guidance of the theory of "Yang turns into Qi and Yin forms" in ,Suwen. Yinyang Yingxiang Dalun, we believe that the pathogenesis of colorectal cancer is Yang deficiency, Yin forming too much, Yin and Yang losing its standard, and the loss of Yuan Yang produces pathological products such as Qi stagnation, blood stasis and phlegm turbidity. The pathological changes of "Yang deficiency as the root and Yin excess as the standard" were formed due to the adhesion of the intestine. To summarize the experience of Professor TANG Nong of Huoshen School in the treatment of colorectal cancer, taking "the second treatment" as the treatment criterion. In clinical practice, ginger, osmanthus and Rhizoma Aconiti are used skillfully, that is to say, Guizhi is used to clear and disperse, warming and dredging middle and upper Jiao is used to "remove its blood vessels" and then Sini method is used to warm and consolidate the lower Jiao, warm and support Yuan Yang, and then benefiting essence is used to fill marrow and cultivate the root. The method is to make Yang from the bottom to the top, from the inside to the outside layer warm, Yin from the top to the bottom, from the outside to the inside layer clear, Yin and Yang return to their standard, rise and fall orderly. In order to maintain the normal life of "dynamic equilibrium of Yin and Yang" and "Yin and Yang harmony", traditional Chinese medicine has unique advantages in the treatment of tumor. Therefore, to explore the etiology, pathogenesis and treatment of colorectal cancer based on the thought of supporting Yang will provide the basis for the clinical treatment of colorectal cancer.