The balance of yin and yang of the human body depends on the coordination of the rise and fall of qi, and the spleen and stomach is the hub of the rise and fall of human body qi. When Professor Huang Zhengde applied the theory of ascending and descending in clinic, he always focused on spleen and stomach, and advocated ascending and descending, especially Shengyang Yiwei decoction for differential treatment of various internal miscellaneous diseases, not only limited to the typical diseases of spleen and stomach, such as stomachache, fullness, noise, vomiting, diarrhea, etc., all diseases belong to the pathogenesis of ascending and descending disorders, which can be treated based on syndrome differentiation, and different diseases can be treated with the same treatment. To expound Professor Huang Zhengde academic thought and clinical experience in the application of lifting theory, and 3 cases are attached to prove it.