A Case of Diagnosis and Treatment of Non-alcoholic Steatohepatitis
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1.Department of Hepatology, Xiamen Hospital of Traditional Chinese Medicine(TCM), Xiamen 361009, China
2.Department of Massage, Xiamen Hospital of TCM, Xiamen 361009, China
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郑晓婷,阮家祥,唐金模,等.非酒精性脂肪性肝炎诊治验案一则[DB/OL].(2023-11-13)[2023-11-13].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43867801&Fpath=home&index=0&lang=zh
ZHENG Xiaoting,RUAN Jiaxiang,TANG Jinmo,et al.A Case of Diagnosis and Treatment of Non-alcoholic Steatohepatitis[J].,
郑晓婷,阮家祥,唐金模,等.非酒精性脂肪性肝炎诊治验案一则[DB/OL].(2023-11-13)[2023-11-13].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43867801&Fpath=home&index=0&lang=zh DOI:
ZHENG Xiaoting,RUAN Jiaxiang,TANG Jinmo,et al.A Case of Diagnosis and Treatment of Non-alcoholic Steatohepatitis[J]., DOI:.
病史摘要,2,患者,林某,男,22岁,未婚,音乐老师。2021年2月24日以“发现脂肪肝伴反复肝功能异常3月余,乏力1周”为主诉就诊。入院前3个月体检发现肝功能异常:ALT 68 U/L,AST 88 U/L,GGT 163 U/L,ALP 135 U/L。彩超示:脂肪肝。未系统诊治。入院前1周因运动后出现乏力伴右膝关节疼痛,活动不利,膝关节稍肿胀,皮温正常。就诊我院骨科,完善右侧膝关节彩超:外侧支持带肿胀,考虑体重过重导致的膝关节损伤可能。为进一步诊治转诊我科,由门诊拟“脂肪肝”收住入院。辰下:乏力,肝区闷胀,口干口苦,周身困重,右膝关节疼痛,活动不利,纳食尚可,夜寐安,小便色黄量可,大便黏滞量少。入院后完善常规生化全套(2021年2月25日):ALT 356 U/L,AST 282 U/L,GGT 164 U/L,ALP 135 U/L,血糖6.9 mmol/L,TG 2.71 mmol/L,尿酸558.6 μmol/L,余正常。肝组织病理:轻度慢性肝炎G2S1,伴重度脂肪肝(SAF评分7分)。四诊信息:精神欠佳,形体肥胖,体重:112 kg,BMI:37.4 kg/m,2,,腹部膨隆多脂,腹软,无压痛、反跳痛。舌暗红,苔黄腻,舌边有齿痕,舌下络脉Ⅱ°迂曲,脉弦滑。中医诊断 肝癖(湿热蕴结、痰瘀阻络证)。西医诊断 1.非酒精性脂肪性肝炎(G2S1,SAF:7分);2.高尿酸血症;3.高脂血症。干预措施 中医治以清热祛湿,豁痰祛瘀为法,方拟皂术茵陈方加减。待患者肝功能改善后,开展中医无饥饿禁食治疗,综合患者四诊资料,考虑湿热渐去,中阳虚损,水湿停聚,痰瘀互结之证,治以温阳健脾利湿,活血化瘀通络为法,方拟皂术茵陈方合苓桂术甘汤加减,配合穴位埋线、刮痧、针灸等中医特色治疗温阳健脾,化湿止痛。西医予以保肝降酶、止痛等治疗。疗效转归 饮食处方及运动处方相结合,调畅中焦,改善生化及肝组织学,减轻体重,改善脂肪肝。
Summary of case history, The patient Lin is a music teacher, who is 22 years old and unmarried male. On February 24, 2021, he went to the doctor with the chief complaint of "Found fatty liver with repeated abnormal liver function for more than 3 months and fatigue for 1 week". Physical examination 3 months before admission revealed abnormal liver function: ALT 68 U/L, AST 88 U/L, GGT 163 U/L, ALP 135 U/L. Color ultrasound: fatty liver. No systematic diagnosis and treatment. One week before admission, there was fatigue after exercise with pain of right knee joint, poor movement, slight swelling of knee joint, and normal skin temperature. He was admitted to the Department of Orthopedics of our hospital to improve the color ultrasound of the right knee joint: swelling of the lateral support band, considering the possibility of knee joint injury caused by overweight. For further diagnosis and treatment, he was referred to our department and admitted with fatty liver by the outpatient department. Symptoms and signs: the patient is weakness, the liver area is stuffy, the mouth is bitter and dry, the body is heavy, the right knee joint is painful and difficult to activate. He can normal to eat and drink, and sleep well. His urine is yellow and the faces is little but sticky. After admission, the complete set of routine biochemistry was completed (February 25, 2021) : ALT 356 U/L, AST 282 U/L, GGT 164 U/L, ALP 135 U/L, blood glucose: 6.9 mmol/L, TG: 2.71mmol/L, uric acid: 558.6 μmol/L, remaining normal. Liver histopathology: mild chronic hepatitis G2S1 with severe fatty liver (SAF score 7). Four diagnostic information: poor spirit, body fat, abdominal distension, abdominal softness, no tenderness, no rebound pain,weighs 112 kg and the BMI is 37.4 kg/m,2,.The tongue is dark red, the fur is yellow and greasy, there are tooth marks on the tongue edge, the sublingual choroid Ⅱ°is tortuous, the pulse string is slippery.,TCM diagnosis, Hepatophilia (Syndrome of dampness-heat accumulation and phlegm stasis blocking collaterals).,Western medicine diagnosis, 1. Nonalcoholic fatty liver hepatitis (G2S1, SAF:7); 2. Hyperuricemia; 3. Hyperlipidemia.,Therapeutic methods, In the treatment of clearing heat and dispelling dampness, clearing phlegm and removing blood stasis as the method, the prescription to add or subtract Chen formula, syndrome differentiation treatment, add or subtract with the syndrome. After the patient's liver function improved, carry out traditional Chinese medicine without hunger fasting treatment, comprehensive patient's four diagnosis data, considering the syndrome of dampness-heat gradually disappearing, middle-yang deficiency, water dampness-stopping accumulation, phlegm and blood stasis interconnecting, treating with warm Yang invigorating spleen and dampness, promoting blood circulation and removing blood stasis and collateralizing collaterality as the method, the prescription for Zao Zhu Yin Chen Fang and Ling Gui Zhu Gan Tang plus or minus, with acupoint burying, scraping, acupuncture and other traditional Chinese medicine characteristics to treat warm Yang invigorating spleen, dampness-relieving. Western medicine is to protect the liver to reduce enzymes, pain relief and other treatments.,Clinical outcomes, The combination of diet prescription and exercise prescription can regulate middle jiao, improve biochemistry and liver histology, reduce weight and improve fatty liver.
脂肪肝中医无饥饿禁食疗法中医特色治疗
Fatty liverChinese medicine without hunger fasting therapyTCM characteristic treatment
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