Summary of case history,　The patient surnamed Wang, male, was admitted to hospital on September 8, 2019 due to "high fever accompanied by skin erythematous rash for half a month and festering for 6 days". With a history of hepatitis B and cirrhosis, she had been taking lamotrigine orally for epilepsy 2 months ago, and had pruritus on the front limbs for half a month and a little red rash on the palms. Extensive rash and swelling gradually appeared on the face, hands and feet, and quickly involved the whole body.,TCM diagnosis,　Drug toxicity/liver heat toxicity dampness/heat toxicity into the campWestern medicine diagnosis 1. Drug hypersensitivity syndrome 2. Epilepsy 3. Liver cirrhosis (hepatitis B compensatory stage) 4. Skin infection 5. Hypoproteinemia Therapeutic methods,Clinical outcomes,　Herbs in the early stage of clearing heat, cooling blood and drying dampness, detoxification and protecting Yin is the method, and in the late stage of clearing heat and fuzheng and nourishing Yin is the method. Western medicine uses anti-infection, liver protection, nutritional support, glucocorticoid, antiviral treatment, combined with traditional Chinese and Western medicine debridement and dressing change.