Summary of case history,　The patient was admitted to hospital with intermittent dry mouth, polydipsia for more than 6 years, accompanied by abdominal distension and fatigue for 1 month.Previous diabetes for more than 6 years, poor blood glucose control in the past 1 year ;The history of chronic hepatitis B was 20 years, and HBeAg was negative in the past 3 years. There was no abnormality in liver disease-related indicators.After the treatment of integrated traditional Chinese and Western medicine, the patient 's virus was controlled and the liver function was corrected, but the blood glucose was obviously fluctuated by the diet, and the digestive tract symptoms and pleural effusion were repeated.The case of this disease was under the guidance of the academic thought of Zhou Xinyou, a master of Chinese medicine.Combined with the guzhang, pathogenesis and pathological characteristics of tympanites and diabetes.Based on the treatment principle of ' clearing away, tonifying deficiency and removing blood stasis ', it is proposed to focus on tonifying the spleen, which has achieved remarkable clinical efficacy.,TCM diagnosis,　guzhang disease (Spleen and kidney yang deficiency and deficiency stasis syndrome).,Western medicine diagnosis,　1.Decompensated cirrhosis ( Child-pugh B ); 2.Chronic viral hepatitis B; 3.Type 3 diabetes,Therapeutic methods,　1.Traditional Chinese medicine: Zhou Lao prescription No.2 addition and subtraction; 2.Non-drug therapy: acupoint application, Chinese medicine collapse stains, thunder fire moxibustion, liver disease treatment instrument; 3.Western medicine treatment points: general treatment ( diet, emotional, abdominal circumference and body weight ), Etiological treatment ( entecavir antiviral ), anti-inflammatory liver protection ( Shuganning, bicyclol ), nutritional support ( energy mixture ), Treatment of complications ( diuretic detumescence, prevention of infection, correction of hypoproteinemia, elevation of white blood cells and platelets, and treatment of ascites ), Primary disease treatment ( control of blood glucose ), endoscopic treatment ( esophageal-gastric variceal ligation embolization ).,Clinical outcomes,　Dry mouth, polydipsia, abdominal distension, fatigue and other gastrointestinal symptoms and systemic symptoms improved; abdominal positive signs disappeared; liver disease and diabetes related indicators have been improved and controlled.