Treatment of ALK Positive Lung Adenocarcinoma with Traditional Chinese Medicine and Targeted Drugs: A Case Report
1.The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, 518033
2.Shenzhen Hospital of Traditional Chinese Medicine, Shenzhen, 518033
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YE Jinghuan, CHEN Zhuni, XIE Wei. Treatment of ALK Positive Lung Adenocarcinoma with Traditional Chinese Medicine and Targeted Drugs: A Case Report[DB/OL].(2023-10-27)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43166829&Fpath=home&index=0
DOI:
YE Jinghuan, CHEN Zhuni, XIE Wei. Treatment of ALK Positive Lung Adenocarcinoma with Traditional Chinese Medicine and Targeted Drugs: A Case Report[DB/OL].(2023-10-27)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43166829&Fpath=home&index=0DOI:
Treatment of ALK Positive Lung Adenocarcinoma with Traditional Chinese Medicine and Targeted Drugs: A Case Report
Summary of case history, The patient Peng, female, 27 years old, went to the doctor on August 27, 2019 due to "nausea and vomiting after targeted drug therapy for lung adenocarcinoma, and headache for more than 1 month". On July 22, 2018, the patient was diagnosed with "infiltrating adenocarcinoma of the left lung, positive for ALK" in the Department of Respiratory and Critical Care Medicine of Shenzhen Hospital of Traditional Chinese Medicine due to "fever, cough, and pain in the left chest and back". After 1 year of treatment with letinib, nausea, vomiting, headache and other discomfort symptoms occurred, so he came to our hospital for outpatient treatment. Symptoms and signs: the patient coughed, coughed up a small amount of white sputum, shoulder and back pain, occasional chest tightness, nausea and vomiting, fatigue, pale complexion, aversion to cold and warmth, stuffy nose, runny nose, dry mouth, no bitter mouth, double the skin on the palms is flushed, poor appetite, poor sleepiness, dry stools, and frequent urination at night. Red tongue, little fur, thready and weak pulse.,TCM diagnosis, Lung accumulation(phlegm toxin stasis syndrome of deficiency of both qi and yin).,Western medicine diagnosis, left lower lobe malignant tumor (cT1N2M1c IV, ALK positive),.Therapeutic methods, The traditional Chinese medicine treatment is based on replenishing qi and nourishing yin, resolving phlegm and dispelling stagnation, and is treated with modified formulas for nourishing qi and nourishing yin; western medicine treats with targeted drug alectinib orally.,Clinical outcomes, Nausea and vomiting did not reoccur after the patient took targeted drugs, cough and sputum, shoulder and back pain did not recur, and sleep was good. The patient's condition was stable during outpatient follow-up, and no signs of tumor recurrence were found.
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