Summary of case history,　The patient is a middle-aged woman,her acne began to occur frequently in the winter three years ago,the face is covered with dark red itchy papules,the forehead, cheeks, mouth, jaw and other parts are particularly serious.The new acne is accompanied by white pus heads and patches of nodules and cysts,acne has deep roots, recurrent attacks.The patient is poor diet and sleep, fear of cold and fatigue.She used to take western medicine and traditional Chinese medicine intermittently, but the effect was not good.,TCM diagnosis,　acne, liver, spleen and kidney disorders,Western medicine diagnosis,　moderate acne (grade Ⅱ),Therapeutic methods,　The mainly treatment is to soothing the liver, harmony between spleen and stomach, warming kidney-water.Chinese medicine decoction: used at the first visit is Pujixiaoduyin and Guizhitang,The curative effect is obvious; In the later stage, on the basis of keeping the front, the empirical formula was added and subtracted.2. Ask patients to pay attention to the daily adjustment of mood, avoid staying up late, eat less spicy food.,Clinical outcomes,　After 2 months of treatment, the original papules and nodules in the affected area became smaller or disappeared. The pigment was diluted, the number of acne and the number of acne attacks were significantly reduced. After the patient stopped taking the drug, we followed up for 3 months, and her acne did not recur and all symptoms were cured.