A Case Report of Biochemical Recurrent Ovarian Cancer
1.The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China
2.Departments of Gynecologic Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, China
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CHEN Shenming, CHEN Xiaofeng, XIAO Jing. A Case Report of Biochemical Recurrent Ovarian Cancer[DB/OL].(2023-10-26)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43053465&Fpath=home&index=0
DOI:
CHEN Shenming, CHEN Xiaofeng, XIAO Jing. A Case Report of Biochemical Recurrent Ovarian Cancer[DB/OL].(2023-10-26)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43053465&Fpath=home&index=0DOI:
A Case Report of Biochemical Recurrent Ovarian Cancer
Summary of case history, A 28-year-old woman was diagnosed with a moderately differentiated mucinous cystadenocarcinoma of the left ovary (FIGO stage IA). The tumor marker CA 72-4 decreased to the normal range after the second cycle, but increased to almost 2 times the upper limit of normal after the fourth chemotherapy cycle, and increased to 7 times the baseline during the subsequent follow-up period. CA72-4 could return to the baseline level after about 6 weeks of acupuncture combined with Chinese medicine therapy after each rise. So far, the patient has finished chemotherapy for 6 years and completed acupuncture combine with Chinese medicine treatments for 4 years, and is still in a disease-free state. This case emphasizes the potential utility of acupuncture combine with traditional Chinese medicine as a treatment scheme for biochemical recurrence of ovarian cancer and deserves further study.,TCM diagnosis, ovarian cancer; spleen and kidney yang deficiency, blood stasis and heat accumulation,Western medicine diagnosis, moderately differentiated mucinous cystadenocarcinoma of ovary(FIGO stage IA),Therapeutic methods, pulse acupuncture and traditional Chinese herbal medicine,Clinical outcomes, disease-free survival,>,6 y,.
关键词
卵巢癌生化复发中药病例报告切脉针灸
Keywords
ovarian cancerbiochemical recurrencetraditional Chinese medicinecase reportpuls acupunctureChinese medicine
references
Hising C, Anjegard IM, Einhorn N. Clinical relevance of the CA 125 assay in monitoring of ovarian cancer patients[J]. Am J Clin Oncol. 1991;14:111–4.
Tuxen MK, Soletormos G, Dombernowsky P. Serum tumor marker CA 125 for monitoring ovarian cancer during follow-up[J]. Scand J Clin Lab Invest. 2002;62:177–88.
Rustin GJ, van der Burg ME, Griffin CL, et al. Early versus delayed treatment of relapsed ovarian cancer: a randomised trial[J].Lancet 2010,376:1155-1163.
Kristeleit R, Davidenko I, Shirinkin V, et al. A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)-only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancer[J]. Gynecol Oncol. 2017;146(3):484-490.
Wang Z, Huang Y, Long L, et al. Apatinib treatment efficiently delays biochemical-only recurrent ovarian cancer progression[J]. J Ovarian Res. 2021;14(1):91.
Ray-Coquard I, Pautier P, Pignata S, et al. Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer[J]. N Engl J Med, 2019, 381(25): 2416-2428.
Penson R T, Valencia R V, Cibula D, et al. Olaparib Versus Nonplatinum Chemotherapy in Patients with Platinum-Sensitive Relapsed Ovarian Cancer and a Germline BRCA1/2 Mutation (SOLO3): A Randomized Phase III Trial[J]. J Clin Oncol, 2020, 38(11): 1164-1174.
Vetter M HHays J L. Use of Targeted Therapeutics in Epithelial Ovarian Cancer: A Review of Current Literature and Future Directions[J]. Clin Ther, 2018, 40(3): 361-371.