Summary of case history,　Main complaint: right lower limb cramp for 20 years, aggravated for 2 years. Current medical history: 20 years ago, the patient had no obvious inducement to have cramps in the right lower limb, and had frequent attacks at night, accompanied by heavy and fatigue of both lower limbs. After taking "Caltrate" by herself, the symptoms were improved. Six years ago, the hospital diagnosed "venous insufficiency of both lower limbs". In the past 2 years, the symptoms have been aggravated, and the right lower limb cramps have been 5~6 times / day, especially at night. There is no obvious relief after taking "Caltrate". The following symptoms are seen: the veins of both lower extremities are tortuous and dilated, with local clumps, especially on the right side; Mild concave edema of both lower extremities, aggravation of heaviness after activity and fatigue; Dry mouth, bitter mouth, Normal appetite, poor sleep, urination, dry stool; The tongue is pale, the moss is thin and yellowish, and the pulse is thin. The previous history of hypertension was 10 years, up to 150/110 mmhg; The history of type 2 diabetes is 10 years, and the current hypoglycemic regimen: metformin 0.5g bid, Acarbose Tablets 50mg tid.,TCM diagnosis,　convulsions,syndrome of deficiency of yin and blood; edema, dampness and blood stasis blocking collaterals syndrome.,Western medicine diagnosis,　muscle spasm of right lower limb, venous insufficiency of lower limb, varicose veins of lower limb, hypertension grade 1 (moderate risk), type 2 diabetes, diabetes peripheral neuropathy.,Therapeutic methods,　Oral Chinese medicine granules, combined with acupuncture therapy. antihypertensive drugs are not given for the time being, and hypoglycemic drugs are continued. Wear pressure gradient elastic socks, lift the affected limb during rest. exercise properly, and eat regularly.,Clinical outcomes,　After oral administration of traditional Chinese medicine and acupuncture treatment, the patient's leg cramp symptoms were significantly improved, occasionally 1~2 times a month, and the sleep quality was greatly improved; Varicose veins were still present in both lower limbs, but the symptoms of heaviness and fatigue were reduced, and edema was improved. The follow-up showed that the patient was wearing pressure gradient elastic socks regularly, and the blood pressure and blood sugar were stable; It has stopped taking traditional Chinese medicine and cooperated with outpatient acupuncture treatment to consolidate and delay the further development of the disease.