Summary of case history,　The patient Wang, a 42-year-old female, was admitted to hospital on August 31, 2012 because of "repeated rash for 1 year, cough for 10 days, chest tightness and asthma for 3 days". In September 2011, there was no obvious inducement for the patient to develop multiple dark red skin rashes on the abdomen and front chest, and then gradually involved both hands and fingers. The treatment effect of the local hospital was poor. In June 2012, a purplish red flaky rash appeared on both sides of the upper eyelid and the nose wing of the face, accompanied by periorbital edema. She went to the Dermatology Hospital of the Chinese Academy of Medical Sciences and was diagnosed as "dermatomyositis" after examination. She was treated with glucocorficord and tripterygium glycoside tablets, and the condition was controlled. The patient developed cough without obvious inducement 10 days ago, chest tightness and asthma 3 days ago, which worsened after exercises. After treatment with glucocorficord and antibiotics, the infection was not obviously controlled and respiratory failure occurred. Therefore, she was transferred to the ICU of Nanjing Gulou Hospital on September 5, 2012. The next day, Professor Zhou Zhongying was invited to consult for comprehensive treatment of traditional Chinese and western medicine,.TCM diagnosis,　Pi Bi-syndrome, Sudden asthma (Pathogenic factors shutting Lung Qi syndrome).,Western medicine diagnosis,　Dermatomyositis, interstitial lung disease, pulmonary infection.,Therapeutic methods,　Traditional Chinese medicine treats the disease from pathogenic qi to close the lung, stagnate the lung and block the lung; Western medicine provides non-invasive ventilation, respiratory support, anti-infection and immune support,Clinical outcomes,　The patient's condition improved, and she was transferred from ICU back to the general ward. After discharge, she was followed up regularly in the outpatient department.