Summary of case history,　Mr. Dong, a 67-year-old male, had sigmoid colon cancer with liver metastasis for more than 8 months and was treated with chemotherapy for 16 times. The patient was diagnosed with "sigmoid colon cancer with liver metastasis" in New York Hospital in the United States 8 months ago, and the pathology of colonoscopy showed sigmoid colon invasive medium differentiated adenocarcinoma; immunohistochemistry showed pMMR; CT showed multiple liver metastases. He was admitted to Fujian Cancer Hospital for chemotherapy with irinotecan + raltitrexed and bevacizumab, and has been treated with chemotherapy for 16 times.After recent chemotherapy, diarrhea, nausea, panic, shortness of breath, cold complications are unbearable. After Professor Zhang Xikui ' s admission on February 22,2022, he found that the patient had frequent diarrhea, abdominal distension, sleepiness, nausea, shortness of breath, chills, pale red tongue coating and thin white pulse. Professor Zhang Xikui identified this case as spleen and kidney deficiency syndrome, and treated it with the method of invigorating spleen and warming kidney, and oozing dampness and stopping diarrhea. Shenlingbaizhu Powder was selected for treatment, and all syndromes were relieved.,TCM diagnosis,　cancer-like disease (syndrome of liver dual deficiency of spleen and kidney),Western medicine diagnosis,　hepatic metastasis of sigmoid colon malignancy.,Therapeutic methods,　Modified Shenling Baizhu Powder for 14 days.,Clinical outcomes,　Complications were stopped, ready to continue chemotherapy, told him to insist on taking Chinese medicine with chemotherapy.