Summary of case history,　Patient Qiu, female, 60 years old,. In May 2010, the patient suffered from fatigue. He was sent to the second hospital of Shandong University. The blood creatinine was 402 μmol/L and hemoglobin was 102 G/L. She was sent to the 264 hospital. The blood creatinine was 416 μmol/L. The abdominal color ultrasound showed that both kidneys were atrophic; Diagnosis: chronic renal failure was treated with blood activating and stasis removing drugs, oral folic acid tablets, Bailing Capsules and erythropoietin for more than 20 days. The blood creatinine was tested at the time of discharge. After discharge, the patient was treated with oral folic acid tablets and Chinese herbal medicine. During the 11 years, the patient had been hospitalized in our hospital for many times due to the aggravation of the disease. The blood creatinine slowly increased and fluctuated between 400-820 μmol/L. In the past week, the patient's fatigue and pain in the waist and back were aggravated. For further diagnosis and treatment, she was hospitalized in our department on April 20, 2021. Admission symptoms: tiredness and fatigue, poor appetite, numbness of limbs, weak waist and knees, dark complexion, poor sleep, dry stool, foam in urine, and moderate urine volume. Her tongue is light and dark, the tongue coating is white and greasy, and the pulse is thin.,TCM diagnosis,　Chronic Renal Failure (deficiency of spleen and kidney qi, dampness, turbidity and stasis),Western medicine diagnosis,　Uremic stage of Chronic Renal Failure; Renal anemia,Therapeutic methods,　Traditional Chinese medicine was treated by oral self-made empirical prescription for renal failure, non drug treatment was given by mechanical colon dialysis, and Western medicine was used to correct anemia.,Clinical outcomes,　The patient's symptoms improved and the serum creatinine decreased to 718 μmol/L.