Summary of case history,　Wang, male, 47 years old, was hospitalized in our hospital on October 19, 2007 due to "intermittent fatigue for 12 and a half years, aggravation with jaundice for 17 days" . The patient had a history of chronic hepatitis B for 15 years treated with Adefovir dipivoxil tablets and Entecavir, and had been diagnosed with cirrhosis 12 years ago. About 17 days before admission, there was no obvious cause of slight yellow staining of the sclera, aggravation of fatigue, accompanied by swelling of the liver area, yellow urine, sparse and yellow-brown stools, without fever, nausea and vomiting, and the jaundice was progressively aggravated. After 1 week of treatment with Chinese medicine decoction, the jaundice did not subside significantly, and was admitted to the hospital for further diagnosis and treatment. He had been diagnosed with Hpertension 3 months treated with nifedipine controlled release tablets, but stopped after jaundice appeared.,TCM diagnosis,　He was diagnosed as jaundice, blood stasis of liver and spleen, dampness and heat accumulation syndrome.,Western medicine diagnosis,　He was diagnosed with acute-on-chronic liver failure (type B, intermediate stage), chronic viral hepatitis B, decompensated liver cirrhosis, portal hypertension (splenomegasplenia, peritoneal effusion, esophagogastric varices), child-Pugh grade C liver function, hypertension grade 2 (medium-risk group).,Therapeutic methods,　The patient was treated with a combination of Traditional Chinese and western medicine. Traditional Chinese medicine prescriptions regulate the liver and spleen, promote blood circulation and remove blood stasis, clear heat and dehumidify, while Western medicine gave anti-virus, liver-protecting, diuresis, supplementing coagulation factors and correcting electrolyte disorder.,Clinical outcomes,　After treatment, the patient's jaundice subsided, fatigue improved, liver function improved significantly. After 14 years of follow-up, liver function improved gradually, hepatitis B surface antigen decreased, and the condition was stable.