Summary of case history,　The patient, a 57-year-old male, came to the clinic mainly because of "he was found to have elevated serum uric acid for 16 years and proteinuria for 7 years". The patient was found to have elevated blood uric acid during physical examination 16 years ago, and took orally uric acid lowering drugs intermittently. The details are unknown. Proteinuria was found during physical examination 7 years ago, which was not paid attention to.The patient developed edema of both lower extremities without obvious incentives 5 years ago, which was relieved after oral traditional Chinese medicine treatment. From 2013 to 2017, the edema of both lower extremities increased intermittently, and the diagnosis and treatment were irregular. The patient went to Xi Jing Hospital in July 2018 due to edema of both lower extremities and toe pain. His blood creatinine was 138 μmol/L (53-115 μmol/L), and blood uric acid was 536 μmol/L (150-430 μmol/L), diagnosed as: gout; gouty nephropathy; renal insufficiency azotemia. To benzbromarone, Bailing Capsules, Niaoduqing Granules treatment. After taking the medicine, the pain in the toes was relieved, and the edema of the lower extremities was not relieved significantly, so the patient come to our outpatient department for further diagnosis and treatment. Current symptoms: pain in the toes, conscious swelling of both lower extremities, blurred vision with many sputum, obvious fatigue, back pain, backache, normal appetite and sleep, urination foam, nocturia 2-3 times, stool 1 line per day, forming. Tongue dark red, yellow and greasy fur, with cracks, deep pulse.,TCM diagnosis,　Gout (Turbidity, blood stasis and heat toxicity, obstruction of kidney collaterals, deficiency of kidney essence),Western medicine diagnosis,　gouty nephropathy, Chronic kidney disease stage 3,Therapeutic methods Traditional Chinese medicine,　Clearing heat and reducing turbidity, promoting blood circulation and detoxification, and nourishing kidney essence; western medicine: sodium bicarbonate tablets to promote uric acid excretion, febuxostat tablets to reduce uric acid, and temporary use of celecoxib capsules for pain relief.,Clinical outcomes,　After 133 days of treatment,the patient's toe pain was cured, edema disappeared, blurred vision disappeared, fatigue was relieved, low back pain was significantly improved, serum creatinine decreased to 102.5 μmol/L, blood uric acid decreased to 328 μmol/L, all returned to normal levels.