Summary of case history ,Patient Chang, female, 58 years old, admitted to the Department of Encephalopathy of our hospital on August 10, 2021 due to 'slow movement accompanied by unstable walking for more than one and a half years and aggravated for three months'. One and a half years ago, the patient was treated in a specialized hospital in Beijing because of slow movement, unstable walking, decreased facial expression, which was diagnosed as "Multiple System Atrophy", the patient was given conventional treatment of Western medicine. The symptoms were slightly improved, but there was still unstable walking with unclear speech. In the past three months, the patient felt that the above symptoms were obviously aggravated, in order to delay the progress of the disease and improve the symptoms, he come to our hospital. Symptoms and signs: unstable walking with slow movements, lack of flexibility in the movement of both lower limbs, especially on the right side, pain from the left foot to the hip joint when walking, the speech was not fluent, the pronunciation was unclear, the intonation was reduced, dizziness, upset, emotional anxiety, difficulty in falling asleep, poor sleep quality, occasional cough and asthma, occasional urinary incontinence, frequent urination, urgent urination, a lot of nocturia, 5-6 times a night, dry stool, one line every 2-3 days. the tongue is pale and dark, the tongue coating is white and greasy, the pulse is deep, the ulnar pulse is deep and weak, and the cun pulse is slightly wiry and astringent.,TCM disease and syndrome ,Yinfei Syndrome (Deficiency of Spleen and Kidney, Stagnation of Liver-qi and Blockage of Evil-qi).,Western medicine diagnosis, Multiple System Atrophy.,Therapeutic methods, Traditional Chinese medicine treats the disease by tonifying kidney essence, invigorating spleen and replenishing qi, soothing liver and relieving depression, eliminating evil and dredging collaterals; western medicine treatment with the previous.,Clinical outcomes ,The patient reported that his physical condition improved significantly, his verbal expression improved, his body aches and other discomforts were relieved, his condition was more stable than before, and his quality of life was significantly improved.