This case reports the diagnosis and treatment of a patient with idiopathic oligoasthenospermia, hoping to provide medication experience and reference for clinical treatment of this disease. The patient came to see a doctor with the main complaint of not having children for 4 years after marriage. Western medicine diagnosed male infertility-idiopathic oligoasthenospermia, Chinese medicine diagnosed as oligospermia, syndrome differentiation for kidney deficiency and blood stasis syndrome. Professor Li Haisong's empirical formula is used in the treatment, mainly to tonify the kidney and essence, replenish qi and activate blood circulation. Professor Li believes that the core pathogenesis of this disease is kidney deficiency and blood stasis. At the same time, it will also contain Qi deficiency, spleen deficiency, liver depression, damp heat and other pathological changes. In clinical treatment, the method of invigorating the kidney and activating blood circulation should be used throughout. It is often effective when combined with some products that replenish qi and invigorate the spleen, soothe the liver and relieve depression, and clear away heat and dampness.,Summary of case history ,For 4 years after marriage, had been without contraception, and multiple semen routine were suggestive of "oligoasthenozoospermia".,TCM diagnosis ,Spermatozoa; Syndrome of kidney deficiency and blood stasis.,Western medicine diagnosis ,Male infertility; Oligoasthenozoospermia.,Therapeutic methods ,Treatment principle: tonifying the kidney and filling the essence, supplementing qi and activating blood circulation.Basic treatment: comprehensive treatment, combination of Chinese and Western medicine, internal and external treatment.,Clinical outcomes ,Sperm quality improved significantly and the spouses were followed up for pregnancy.